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Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo

Background: The dystrophin gene has multiple isoforms: full-length dystrophin (dp427) is principally known for its expression in skeletal and cardiac muscle, but is also expressed in the brain, and several internal promoters give rise to shorter, N-terminally truncated isoforms with wider tissue exp...

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Detalles Bibliográficos
Autores principales: Hildyard, John C. W., Crawford, Abbe H., Rawson, Faye, Riddell, Dominique O., Harron, Rachel C. M., Piercy, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372313/
https://www.ncbi.nlm.nih.gov/pubmed/32724863
http://dx.doi.org/10.12688/wellcomeopenres.15762.2