Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms

mAbs are a possible adjunct to vaccination and drugs in treatment of influenza virus infection. However, questions remain whether small animal models accurately predict efficacy in humans. We have established the pig, a large natural host animal for influenza, with many physiological similarities to...

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Detalles Bibliográficos
Autores principales: McNee, Adam, Smith, Trevor R. F., Holzer, Barbara, Clark, Becky, Bessell, Emily, Guibinga, Ghiabe, Brown, Heather, Schultheis, Katherine, Fisher, Paul, Ramos, Stephanie, Nunez, Alejandro, Bernard, Matthieu, Graham, Simon, Martini, Veronica, Chrun, Tiphany, Xiao, Yongli, Kash, John C., Taubenberger, Jeffery K., Elliott, Sarah, Patel, Ami, Beverley, Peter, Rijal, Pramila, Weiner, David B., Townsend, Alain, Broderick, Kate E., Tchilian, Elma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2020
Materias:
Immunotherapy and Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372317/
https://www.ncbi.nlm.nih.gov/pubmed/32591390
http://dx.doi.org/10.4049/jimmunol.2000429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372317/
https://www.ncbi.nlm.nih.gov/pubmed/32591390
http://dx.doi.org/10.4049/jimmunol.2000429

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