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Strategies for Improving Antimicrobial Properties of Stainless Steel

In this review, strategies for improving the antimicrobial properties of stainless steel (SS) are presented. The main focus given is to present current strategies for surface modification of SS, which alter surface characteristics in terms of surface chemistry, topography and wettability/surface cha...

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Autores principales: Resnik, Matic, Benčina, Metka, Levičnik, Eva, Rawat, Niharika, Iglič, Aleš, Junkar, Ita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372344/
https://www.ncbi.nlm.nih.gov/pubmed/32630130
http://dx.doi.org/10.3390/ma13132944
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author Resnik, Matic
Benčina, Metka
Levičnik, Eva
Rawat, Niharika
Iglič, Aleš
Junkar, Ita
author_facet Resnik, Matic
Benčina, Metka
Levičnik, Eva
Rawat, Niharika
Iglič, Aleš
Junkar, Ita
author_sort Resnik, Matic
collection PubMed
description In this review, strategies for improving the antimicrobial properties of stainless steel (SS) are presented. The main focus given is to present current strategies for surface modification of SS, which alter surface characteristics in terms of surface chemistry, topography and wettability/surface charge, without influencing the bulk attributes of the material. As SS exhibits excellent mechanical properties and satisfactory biocompatibility, it is one of the most frequently used materials in medical applications. It is widely used as a material for fabricating orthopedic prosthesis, cardiovascular stents/valves and recently also for three dimensional (3D) printing of custom made implants. Despite its good mechanical properties, SS lacks desired biofunctionality, which makes it prone to bacterial adhesion and biofilm formation. Due to increased resistance of bacteria to antibiotics, it is imperative to achieve antibacterial properties of implants. Thus, many different approaches were proposed and are discussed herein. Emphasis is given on novel approaches based on treatment with highly reactive plasma, which may alter SS topography, chemistry and wettability under appropriate treatment conditions. This review aims to present and critically discuss different approaches and propose novel possibilities for surface modification of SS by using highly reactive gaseous plasma in order to obtain a desired biological response.
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spelling pubmed-73723442020-08-05 Strategies for Improving Antimicrobial Properties of Stainless Steel Resnik, Matic Benčina, Metka Levičnik, Eva Rawat, Niharika Iglič, Aleš Junkar, Ita Materials (Basel) Review In this review, strategies for improving the antimicrobial properties of stainless steel (SS) are presented. The main focus given is to present current strategies for surface modification of SS, which alter surface characteristics in terms of surface chemistry, topography and wettability/surface charge, without influencing the bulk attributes of the material. As SS exhibits excellent mechanical properties and satisfactory biocompatibility, it is one of the most frequently used materials in medical applications. It is widely used as a material for fabricating orthopedic prosthesis, cardiovascular stents/valves and recently also for three dimensional (3D) printing of custom made implants. Despite its good mechanical properties, SS lacks desired biofunctionality, which makes it prone to bacterial adhesion and biofilm formation. Due to increased resistance of bacteria to antibiotics, it is imperative to achieve antibacterial properties of implants. Thus, many different approaches were proposed and are discussed herein. Emphasis is given on novel approaches based on treatment with highly reactive plasma, which may alter SS topography, chemistry and wettability under appropriate treatment conditions. This review aims to present and critically discuss different approaches and propose novel possibilities for surface modification of SS by using highly reactive gaseous plasma in order to obtain a desired biological response. MDPI 2020-06-30 /pmc/articles/PMC7372344/ /pubmed/32630130 http://dx.doi.org/10.3390/ma13132944 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Resnik, Matic
Benčina, Metka
Levičnik, Eva
Rawat, Niharika
Iglič, Aleš
Junkar, Ita
Strategies for Improving Antimicrobial Properties of Stainless Steel
title Strategies for Improving Antimicrobial Properties of Stainless Steel
title_full Strategies for Improving Antimicrobial Properties of Stainless Steel
title_fullStr Strategies for Improving Antimicrobial Properties of Stainless Steel
title_full_unstemmed Strategies for Improving Antimicrobial Properties of Stainless Steel
title_short Strategies for Improving Antimicrobial Properties of Stainless Steel
title_sort strategies for improving antimicrobial properties of stainless steel
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372344/
https://www.ncbi.nlm.nih.gov/pubmed/32630130
http://dx.doi.org/10.3390/ma13132944
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