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Predicting Cancer Tissue-of-Origin by a Machine Learning Method Using DNA Somatic Mutation Data

Patients with carcinoma of unknown primary (CUP) account for 3–5% of all cancer cases. A large number of metastatic cancers require further diagnosis to determine their tissue of origin. However, diagnosis of CUP and identification of its primary site are challenging. Previous studies have suggested...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojun, Li, Lianxing, Peng, Lihong, Wang, Bo, Lang, Jidong, Lu, Qingqing, Zhang, Xizhe, Sun, Yi, Tian, Geng, Zhang, Huajun, Zhou, Liqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372518/
https://www.ncbi.nlm.nih.gov/pubmed/32760423
http://dx.doi.org/10.3389/fgene.2020.00674