High-Throughput Analysis of Fluorescently Labeled N-Glycans Derived from Biotherapeutics Using an Automated LC-MS-Based Solution

Protein glycosylation can impact the efficacy and safety of biotherapeutics and therefore needs to be well characterized and monitored throughout the drug product life cycle. Glycosylation is commonly assessed by fluorescent labeling of released glycans, which provides comprehensive information of t...

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Detalles Bibliográficos
Autores principales: Zhang, Ximo, Reed, Corey E., Birdsall, Robert E., Yu, Ying Qing, Chen, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372583/
https://www.ncbi.nlm.nih.gov/pubmed/32458729
http://dx.doi.org/10.1177/2472630320922803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372583/
https://www.ncbi.nlm.nih.gov/pubmed/32458729
http://dx.doi.org/10.1177/2472630320922803

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