Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension

Pulmonary arterial hypertension is a fatal disorder of the lung circulation in which accumulation of vascular cells progressively obliterates the pulmonary arterioles. This results in sustained elevation in pulmonary artery pressure leading eventually to right heart failure. Approximately, 80% of fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Lu, Yang, Xudong, Southwood, Mark, Moore, Stephen, Crosby, Alexi, Upton, Paul D., Dunmore, Benjamin J., Morrell, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372630/
https://www.ncbi.nlm.nih.gov/pubmed/32733669
http://dx.doi.org/10.1177/2045894020935783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372630/
https://www.ncbi.nlm.nih.gov/pubmed/32733669
http://dx.doi.org/10.1177/2045894020935783

Ejemplares similares