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CROSSLINKER CONCENTRATION CONTROLS TGFβ−3 RELEASE AND ANNULUS FIBROSUS CELL APOPTOSIS IN GENIPIN-CROSSLINKED FIBRIN HYDROGELS

Back pain is a leading cause of global disability associated with intervertebral disc (IVD) pathologies. Discectomy alleviates disabling pain caused by IVD herniation without repairing annulus fibrosus (AF) defects, which can cause accelerated degeneration and recurrent pain. Biological therapies sh...

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Detalles Bibliográficos
Autores principales: Panebianco, C.J., DiStefano, T.J., Mui, B., Hom, W.W., Iatridis, J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372750/
https://www.ncbi.nlm.nih.gov/pubmed/32396210
http://dx.doi.org/10.22203/eCM.v039a14