SpectralTAD: an R package for defining a hierarchy of topologically associated domains using spectral clustering

BACKGROUND: The three-dimensional (3D) structure of the genome plays a crucial role in gene expression regulation. Chromatin conformation capture technologies (Hi-C) have revealed that the genome is organized in a hierarchy of topologically associated domains (TADs), sub-TADs, and chromatin loops. I...

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Detalles Bibliográficos
Autores principales: Cresswell, Kellen G., Stansfield, John C., Dozmorov, Mikhail G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372752/
https://www.ncbi.nlm.nih.gov/pubmed/32689928
http://dx.doi.org/10.1186/s12859-020-03652-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372752/
https://www.ncbi.nlm.nih.gov/pubmed/32689928
http://dx.doi.org/10.1186/s12859-020-03652-w

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