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SpectralTAD: an R package for defining a hierarchy of topologically associated domains using spectral clustering
BACKGROUND: The three-dimensional (3D) structure of the genome plays a crucial role in gene expression regulation. Chromatin conformation capture technologies (Hi-C) have revealed that the genome is organized in a hierarchy of topologically associated domains (TADs), sub-TADs, and chromatin loops. I...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372752/ https://www.ncbi.nlm.nih.gov/pubmed/32689928 http://dx.doi.org/10.1186/s12859-020-03652-w |