Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study

BACKGROUND: There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions. METHODS: We used computational machine learning to derive a rule-out blood transcriptomic signature of bacterial infecti...

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Detalles Bibliográficos
Autores principales: Sampson, Dayle, Yager, Thomas D., Fox, Brian, Shallcross, Laura, McHugh, Leo, Seldon, Therese, Rapisarda, Antony, Brandon, Richard B., Navalkar, Krupa, Simpson, Nandi, Stafford, Sian, Gil, Eliza, Venturini, Cristina, Tsaliki, Evi, Roe, Jennifer, Chain, Benjamin, Noursadeghi, Mahdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372897/
https://www.ncbi.nlm.nih.gov/pubmed/32690014
http://dx.doi.org/10.1186/s12916-020-01653-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372897/
https://www.ncbi.nlm.nih.gov/pubmed/32690014
http://dx.doi.org/10.1186/s12916-020-01653-3

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