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Lyssavirus Vaccine with a Chimeric Glycoprotein Protects across Phylogroups

Rabies is nearly 100% lethal in the absence of treatment, killing an estimated 59,000 people annually. Vaccines and biologics are highly efficacious when administered properly. Sixteen rabies-related viruses (lyssaviruses) are similarly lethal, but some are divergent enough to evade protection from...

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Detalles Bibliográficos
Autores principales: Fisher, Christine R., Lowe, David E., Smith, Todd G., Yang, Yong, Hutson, Christina L., Wirblich, Christoph, Cingolani, Gino, Schnell, Matthias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373069/
https://www.ncbi.nlm.nih.gov/pubmed/32697993
http://dx.doi.org/10.1016/j.celrep.2020.107920