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Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

COVID-19 patients show varying severity of the disease ranging from asymptomatic to requiring intensive care. Although a number of SARS-CoV-2 specific monoclonal antibodies have been identified, we still lack an understanding of the overall landscape of B-cell receptor (BCR) repertoires in COVID-19...

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Detalles Bibliográficos
Autores principales: Montague, Zachary, Lv, Huibin, Otwinowski, Jakub, DeWitt, William S., Isacchini, Giulio, Yip, Garrick K., Ng, Wilson W., Tsang, Owen Tak-Yin, Yuan, Meng, Liu, Hejun, Wilson, Ian A., Peiris, J. S. Malik, Wu, Nicholas C., Nourmohammad, Armita, Mok, Chris Ka Pun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373151/
https://www.ncbi.nlm.nih.gov/pubmed/32699862
http://dx.doi.org/10.1101/2020.07.13.20153114