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Innovative Therapeutic and Delivery Approaches Using Nanotechnology to Correct Splicing Defects Underlying Disease

Alternative splicing of pre-mRNA contributes strongly to the diversity of cell- and tissue-specific protein expression patterns. Global transcriptome analyses have suggested that >90% of human multiexon genes are alternatively spliced. Alterations in the splicing process cause missplicing events...

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Detalles Bibliográficos
Autores principales: Suñé-Pou, Marc, Limeres, María J., Moreno-Castro, Cristina, Hernández-Munain, Cristina, Suñé-Negre, Josep M., Cuestas, María L., Suñé, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373156/
https://www.ncbi.nlm.nih.gov/pubmed/32760425
http://dx.doi.org/10.3389/fgene.2020.00731