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The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans

The opportunistic fungal pathogen Cryptococcus neoformans must adapt to the mammalian environment to establish an infection. Proteins facilitating adaptation to novel environments, such as chaperones, may be required for virulence. In this study, we identified a novel mitochondrial co-chaperone, Mrj...

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Detalles Bibliográficos
Autores principales: Horianopoulos, Linda C., Hu, Guanggan, Caza, Mélissa, Schmitt, Kerstin, Overby, Peter, Johnson, James D., Valerius, Oliver, Braus, Gerhard H., Kronstad, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373193/
https://www.ncbi.nlm.nih.gov/pubmed/32518190
http://dx.doi.org/10.1128/mBio.01127-20