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The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans
The opportunistic fungal pathogen Cryptococcus neoformans must adapt to the mammalian environment to establish an infection. Proteins facilitating adaptation to novel environments, such as chaperones, may be required for virulence. In this study, we identified a novel mitochondrial co-chaperone, Mrj...
Autores principales: | Horianopoulos, Linda C., Hu, Guanggan, Caza, Mélissa, Schmitt, Kerstin, Overby, Peter, Johnson, James D., Valerius, Oliver, Braus, Gerhard H., Kronstad, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373193/ https://www.ncbi.nlm.nih.gov/pubmed/32518190 http://dx.doi.org/10.1128/mBio.01127-20 |
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