Key Positions of HIV-1 Env and Signatures of Vaccine Efficacy Show Gradual Reduction of Population Founder Effects at the Clade and Regional Levels

HIV-1 group M was transmitted to humans nearly one century ago. The virus has since evolved to form distinct clades, which spread to different regions of the world. The envelope glycoproteins (Envs) of HIV-1 have rapidly diversified in all infected populations. We examined whether key antigenic site...

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Detalles Bibliográficos
Autores principales: Han, Changze, Johnson, Jacklyn, Dong, Rentian, Kandula, Raghavendranath, Kort, Alexa, Wong, Maria, Yang, Tianbao, Breheny, Patrick J., Brown, Grant D., Haim, Hillel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373194/
https://www.ncbi.nlm.nih.gov/pubmed/32518179
http://dx.doi.org/10.1128/mBio.00126-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373194/
https://www.ncbi.nlm.nih.gov/pubmed/32518179
http://dx.doi.org/10.1128/mBio.00126-20

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