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Key Positions of HIV-1 Env and Signatures of Vaccine Efficacy Show Gradual Reduction of Population Founder Effects at the Clade and Regional Levels
HIV-1 group M was transmitted to humans nearly one century ago. The virus has since evolved to form distinct clades, which spread to different regions of the world. The envelope glycoproteins (Envs) of HIV-1 have rapidly diversified in all infected populations. We examined whether key antigenic site...
Autores principales: | Han, Changze, Johnson, Jacklyn, Dong, Rentian, Kandula, Raghavendranath, Kort, Alexa, Wong, Maria, Yang, Tianbao, Breheny, Patrick J., Brown, Grant D., Haim, Hillel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373194/ https://www.ncbi.nlm.nih.gov/pubmed/32518179 http://dx.doi.org/10.1128/mBio.00126-20 |
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