Inhibition of the Super Elongation Complex Suppresses Herpes Simplex Virus Immediate Early Gene Expression, Lytic Infection, and Reactivation from Latency

Induction of herpes simplex virus (HSV) immediate early (IE) gene transcription promotes the initiation of lytic infection and reactivation from latency in sensory neurons. IE genes are transcribed by the cellular RNA polymerase II (RNAPII) and regulated by multiple transcription factors and coactiv...

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Detalles Bibliográficos
Autores principales: Alfonso-Dunn, Roberto, Arbuckle, Jesse H., Vogel, Jodi L., Kristie, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373197/
https://www.ncbi.nlm.nih.gov/pubmed/32518191
http://dx.doi.org/10.1128/mBio.01216-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373197/
https://www.ncbi.nlm.nih.gov/pubmed/32518191
http://dx.doi.org/10.1128/mBio.01216-20

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