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Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?
The opioid receptors are a family of G-protein coupled receptors (GPCRs) with close structural homology. The opioid receptors are activated by a variety of endogenous opioid neuropeptides, principally β-endorphin, dynorphins, leu- and met-enkephalins. The clinical potential of targeting opioid recep...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373229/ https://www.ncbi.nlm.nih.gov/pubmed/32714584 http://dx.doi.org/10.1042/NS20170145 |