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A role for TGFβ signalling in medium spiny neuron differentiation of human pluripotent stem cells

Activin A and other TGFβ family members have been shown to exhibit a certain degree of promiscuity between their family of receptors. We previously developed an efficient differentiation protocol using Activin A to obtain medium spiny neurons (MSNs) from human pluripotent stem cells (hPSCs). However...

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Detalles Bibliográficos
Autores principales: Fjodorova, Marija, Noakes, Zoe, Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373249/
https://www.ncbi.nlm.nih.gov/pubmed/32714602
http://dx.doi.org/10.1042/NS20200004