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Heme oxygenase-1 in protozoan infections: A tale of resistance and disease tolerance

Heme oxygenase (HO-1) mediates the enzymatic cleavage of heme, a molecule with proinflammatory and prooxidant properties. HO-1 activity deeply impacts host capacity to tolerate infection through reduction of tissue damage or affecting resistance, the ability of the host to control pathogen loads. In...

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Detalles Bibliográficos
Autores principales: Silva, Rafael C. M. C., Travassos, Leonardo H., Paiva, Claudia N., Bozza, Marcelo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373268/
https://www.ncbi.nlm.nih.gov/pubmed/32692767
http://dx.doi.org/10.1371/journal.ppat.1008599