The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer

The definitive characterization of common cancer stem cell (CSCs) subpopulations in breast cancer subtypes with distinct genotypic and phenotypic features remains an ongoing challenge. In this study, we have used a non-biased genome wide screening approach to identify transcriptional networks that m...

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Detalles Bibliográficos
Autores principales: Walsh, Claire A., Akrap, Nina, Garre, Elena, Magnusson, Ylva, Harrison, Hannah, Andersson, Daniel, Jonasson, Emma, Rafnsdottir, Svanheidur, Choudhry, Hani, Buffa, Francesca, Ragoussis, Jiannis, Ståhlberg, Anders, Harris, Adrian, Landberg, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373278/
https://www.ncbi.nlm.nih.gov/pubmed/32692762
http://dx.doi.org/10.1371/journal.pone.0236187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373278/
https://www.ncbi.nlm.nih.gov/pubmed/32692762
http://dx.doi.org/10.1371/journal.pone.0236187

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