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The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer
The definitive characterization of common cancer stem cell (CSCs) subpopulations in breast cancer subtypes with distinct genotypic and phenotypic features remains an ongoing challenge. In this study, we have used a non-biased genome wide screening approach to identify transcriptional networks that m...
Autores principales: | Walsh, Claire A., Akrap, Nina, Garre, Elena, Magnusson, Ylva, Harrison, Hannah, Andersson, Daniel, Jonasson, Emma, Rafnsdottir, Svanheidur, Choudhry, Hani, Buffa, Francesca, Ragoussis, Jiannis, Ståhlberg, Anders, Harris, Adrian, Landberg, Göran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373278/ https://www.ncbi.nlm.nih.gov/pubmed/32692762 http://dx.doi.org/10.1371/journal.pone.0236187 |
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