A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons

The RNA exosome is an evolutionarily-conserved ribonuclease complex critically important for precise processing and/or complete degradation of a variety of cellular RNAs. The recent discovery that mutations in genes encoding structural RNA exosome subunits cause tissue-specific diseases makes defini...

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Detalles Bibliográficos
Autores principales: Morton, Derrick J., Jalloh, Binta, Kim, Lily, Kremsky, Isaac, Nair, Rishi J., Nguyen, Khuong B., Rounds, J. Christopher, Sterrett, Maria C., Brown, Brianna, Le, Thalia, Karkare, Maya C., McGaughey, Kathryn D., Sheng, Shaoyi, Leung, Sara W., Fasken, Milo B., Moberg, Kenneth H., Corbett, Anita H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373318/
https://www.ncbi.nlm.nih.gov/pubmed/32645003
http://dx.doi.org/10.1371/journal.pgen.1008901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373318/
https://www.ncbi.nlm.nih.gov/pubmed/32645003
http://dx.doi.org/10.1371/journal.pgen.1008901

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