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Androgen receptor signaling in the lungs mitigates inflammation and improves the outcome of influenza in mice

Circulating androgens can modulate immune cell activity, but the impact of androgens on viral pathogenesis remains unclear. Previous data demonstrate that testosterone reduces the severity of influenza A virus (IAV) infection in male mice by mitigating pulmonary inflammation rather than by affecting...

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Detalles Bibliográficos
Autores principales: vom Steeg, Landon G., Dhakal, Santosh, Woldetsadik, Yishak A., Park, Han-Sol, Mulka, Kathleen R., Reilly, Emma C., Topham, David J., Klein, Sabra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373319/
https://www.ncbi.nlm.nih.gov/pubmed/32645119
http://dx.doi.org/10.1371/journal.ppat.1008506