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A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells inhibiting tumor growth

BACKGROUND: Immune checkpoint blocker (ICB) therapy has shown survival benefits for some patients with cancer. Nevertheless, many individuals remain refractory or acquire resistance to treatment, motivating the exploration of complementary immunotherapies. Accordingly, cancer vaccines offer an attra...

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Detalles Bibliográficos
Autores principales: Gleisner, María Alejandra, Pereda, Cristián, Tittarelli, Andrés, Navarrete, Mariela, Fuentes, Camila, Ávalos, Ignacio, Tempio, Fabian, Araya, Juan Pablo, Becker, María Inés, González, Fermín Eduardo, López, Mercedes Natalia, Salazar-Onfray, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373330/
https://www.ncbi.nlm.nih.gov/pubmed/32690772
http://dx.doi.org/10.1136/jitc-2020-000999