Preconditioning with L-Ala-Gln reduces the expression of inflammatory markers (TNF-α, NF-κB, IL-6 and HO-1) in an injury animal model of cerebrovascular ischemia in Meriones unguiculatus (gerbils)

PURPOSE: To evaluate the neuroprotective effect of L-alanyl-glutamine in a gerbil model of brain ischemia-reperfusion injury based on immunohistochemical quantification of pro-inflammatory and cell activation biomarkers (TNF-α, NF-κB, IL-6 and HO-1). METHODS: Male gerbils weighing 100-180 g were pre...

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Detalles Bibliográficos
Autores principales: de Oliveira, Leidelamar Rosário Alves, Albuquerque, Andréa de Oliveira, Silva, Cícero Igor Simões Moura, Silva, Jussara Mathiele, Casadevall, Meyssa Quezado de Figueiredo Cavalcante, de Azevedo, Orleancio Gomes Ripardo, Albuquerque, Vilma Leite de Souza Pires, de Vasconcelos, Paulo Roberto Leitão
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373374/
https://www.ncbi.nlm.nih.gov/pubmed/32696813
http://dx.doi.org/10.1590/s0102-865020200060000001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373374/
https://www.ncbi.nlm.nih.gov/pubmed/32696813
http://dx.doi.org/10.1590/s0102-865020200060000001

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