Cargando…

New insights into the mechanism of dynein motor regulation by lissencephaly-1

Lissencephaly (‘smooth brain’) is a severe brain disease associated with numerous symptoms, including cognitive impairment, and shortened lifespan. The main causative gene of this disease – lissencephaly-1 (LIS1) – has been a focus of intense scrutiny since its first identification almost 30 years a...

Descripción completa

Detalles Bibliográficos
Autores principales: Markus, Steven M, Marzo, Matthew G, McKenney, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373426/
https://www.ncbi.nlm.nih.gov/pubmed/32692650
http://dx.doi.org/10.7554/eLife.59737