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Clustered gamma-protocadherins regulate cortical interneuron programmed cell death

Cortical function critically depends on inhibitory/excitatory balance. Cortical inhibitory interneurons (cINs) are born in the ventral forebrain and migrate into cortex, where their numbers are adjusted by programmed cell death. Here, we show that loss of clustered gamma protocadherins (Pcdhg), but...

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Detalles Bibliográficos
Autores principales: Mancia Leon, Walter R, Spatazza, Julien, Rakela, Benjamin, Chatterjee, Ankita, Pande, Viraj, Maniatis, Tom, Hasenstaub, Andrea R, Stryker, Michael P, Alvarez-Buylla, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373431/
https://www.ncbi.nlm.nih.gov/pubmed/32633719
http://dx.doi.org/10.7554/eLife.55374