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Potential strategy for assessing QT/QTc interval for drugs that produce rapid changes in heart rate: Electrocardiographic assessment of the effects of intravenous remimazolam on cardiac repolarization
AIMS: Remimazolam is a new, ultra‐short‐acting benzodiazepine developed for intravenous (IV) use during procedural sedation and in general anaesthesia. Two trials were conducted to characterize its effects on cardiac repolarization. METHODS: A thorough QT/QTc (TQT) study assessed electrocardiography...
Autores principales: | Kleiman, Robert B., Darpo, Borje, Thorn, Michael, Stoehr, Thomas, Schippers, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373701/ https://www.ncbi.nlm.nih.gov/pubmed/32144789 http://dx.doi.org/10.1111/bcp.14270 |
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