Enhanced AmB Production in Streptomyces nodosus by Fermentation Regulation and Rational Combined Feeding Strategy

Amphotericin B is a clinically important polyene macrolide antibiotic with a broad-spectrum antifungal activity. In this work, the addition of key precursors and differential metabolites, combined with staged fermentation process control strategies, was carried out to improve AmB production. Rationa...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhang, Yu-Han, Chen, Yu, Chen, Kai, Jiang, Sheng-Xian, Huang, Kai, Liu, Zhi-Qiang, Zheng, Yu-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373727/
https://www.ncbi.nlm.nih.gov/pubmed/32760700
http://dx.doi.org/10.3389/fbioe.2020.00597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373727/
https://www.ncbi.nlm.nih.gov/pubmed/32760700
http://dx.doi.org/10.3389/fbioe.2020.00597

Ejemplares similares