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A Novel Nonsense Mutation of ABCA8 in a Han-Chinese Family With ASCVD Leads to the Reduction of HDL-c Levels

Arteriosclerotic cardiovascular disease (ASCVD) is one of the major causes of death worldwide and most commonly develops as a result of atherosclerosis (AS). As we all know, dyslipidemia is a leading pathogenic risk factor for ASCVD, which leads to cardiac ischemic injury and myocardial infarction....

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Detalles Bibliográficos
Autores principales: Wang, Chen-Yu, Chen, Ya-Qin, Jin, Jie-Yuan, Du, Ran, Fan, Liang-Liang, Xiang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373792/
https://www.ncbi.nlm.nih.gov/pubmed/32760429
http://dx.doi.org/10.3389/fgene.2020.00755