PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane–Based Neoadjuvant Chemotherapy

PURPOSE: PIK3CA, encoding for subunit p110a of phosphatidylinositol 3 kinase, is frequently mutated in breast cancer. PIK3CA mutation was predictive for pathological complete response (pCR) in human epidermal growth factor 2 positive breast cancer. This study explores the association of PIK3CA mutat...

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Detalles Bibliográficos
Autores principales: Guo, Sanxing, Loibl, Sibylle, von Minckwitz, Gunter, Darb-Esfahani, Silvia, Lederer, Bianca, Denkert, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373870/
https://www.ncbi.nlm.nih.gov/pubmed/32019278
http://dx.doi.org/10.4143/crt.2019.497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373870/
https://www.ncbi.nlm.nih.gov/pubmed/32019278
http://dx.doi.org/10.4143/crt.2019.497

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