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Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test

PURPOSE: Hereditary cancer syndrome means that inherited genetic mutations can increase a person's risk of developing cancer. We assessed the frequency of germline mutations using an next-generation sequencing (NGS)–based multiple-gene panel containing 64 cancer-predisposing genes in Korean bre...

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Detalles Bibliográficos
Autores principales: Shin, Hee-Chul, Lee, Han-Byoel, Yoo, Tae-Kyung, Lee, Eun-Shin, Kim, Ryong Nam, Park, Boyoung, Yoon, Kyong-Ah, Park, Charny, Lee, Eun Sook, Moon, Hyeong-Gon, Noh, Dong-Young, Kong, Sun-Young, Han, Wonshik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373875/
https://www.ncbi.nlm.nih.gov/pubmed/32019277
http://dx.doi.org/10.4143/crt.2019.559