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Inhibition of ATR Increases the Sensitivity to WEE1 Inhibitor in Biliary Tract Cancer
PURPOSE: Currently, the DNA damage response (DDR) pathway represents a key target for new cancer drug development. Advanced biliary tract cancer (BTC) has a poor prognosis because of the lack of efficacious treatment options. Although DNA repair pathway alterations have been reported in many patient...
Autores principales: | Nam, Ah-Rong, Jin, Mei-Hua, Bang, Ju-Hee, Oh, Kyoung-Seok, Seo, Hye-Rim, Oh, Do-Youn, Bang, Yung-Jue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373879/ https://www.ncbi.nlm.nih.gov/pubmed/32311864 http://dx.doi.org/10.4143/crt.2020.080 |
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