Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure

AIMS: The effects of GRK2 inhibition on myocardial metabolism in heart failure (HF) are unchartered. In this work, we evaluated the impact of pharmacological inhibition of GRK2 by a cyclic peptide, C7, on metabolic, biochemical, and functional phenotypes in experimental HF. METHODS AND RESULTS: C7 w...

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Detalles Bibliográficos
Autores principales: Ciccarelli, Michele, Sorriento, Daniela, Fiordelisi, Antonella, Gambardella, Jessica, Franco, Antonietta, del Giudice, Carmine, Sala, Marina, Monti, Maria Gaia, Bertamino, Alessia, Campiglia, Pietro, Oliveti, Marco, Poggio, Paolo, Trinchese, Giovanna, Cavaliere, Gina, Cipolletta, Ersilia, Mollica, Maria Pina, Bonaduce, Domenico, Trimarco, Bruno, Iaccarino, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373898/
https://www.ncbi.nlm.nih.gov/pubmed/32352228
http://dx.doi.org/10.1002/ehf2.12706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373898/
https://www.ncbi.nlm.nih.gov/pubmed/32352228
http://dx.doi.org/10.1002/ehf2.12706

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