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Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

Tightly interlinked feedback regulators control the dynamics of intracellular responses elicited by the activation of signal transduction pathways. Interferon alpha (IFNα) orchestrates antiviral responses in hepatocytes, yet mechanisms that define pathway sensitization in response to prestimulation...

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Detalles Bibliográficos
Autores principales: Kok, Frédérique, Rosenblatt, Marcus, Teusel, Melissa, Nizharadze, Tamar, Gonçalves Magalhães, Vladimir, Dächert, Christopher, Maiwald, Tim, Vlasov, Artyom, Wäsch, Marvin, Tyufekchieva, Silvana, Hoffmann, Katrin, Damm, Georg, Seehofer, Daniel, Boettler, Tobias, Binder, Marco, Timmer, Jens, Schilling, Marcel, Klingmüller, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373899/
https://www.ncbi.nlm.nih.gov/pubmed/32696599
http://dx.doi.org/10.15252/msb.20198955