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Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction
Tightly interlinked feedback regulators control the dynamics of intracellular responses elicited by the activation of signal transduction pathways. Interferon alpha (IFNα) orchestrates antiviral responses in hepatocytes, yet mechanisms that define pathway sensitization in response to prestimulation...
Autores principales: | Kok, Frédérique, Rosenblatt, Marcus, Teusel, Melissa, Nizharadze, Tamar, Gonçalves Magalhães, Vladimir, Dächert, Christopher, Maiwald, Tim, Vlasov, Artyom, Wäsch, Marvin, Tyufekchieva, Silvana, Hoffmann, Katrin, Damm, Georg, Seehofer, Daniel, Boettler, Tobias, Binder, Marco, Timmer, Jens, Schilling, Marcel, Klingmüller, Ursula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373899/ https://www.ncbi.nlm.nih.gov/pubmed/32696599 http://dx.doi.org/10.15252/msb.20198955 |
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