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Diabetes mellitus exacerbates post‐myocardial infarction heart failure by reducing sarcolipin promoter methylation

AIMS: Sarcolipin (SLN) is a key regulator of sarcoplasmic reticulum calcium‐ATPase (SERCA)2a, which handles intracellular calcium re‐uptake. This study was aimed to investigate the involvement of SLN in post‐myocardial infarction (MI) heart failure (HF) in diabetes. METHODS AND RESULTS: Diabetes/MI...

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Detalles Bibliográficos
Autores principales: Liu, Zhongwei, Zhang, Yong, Qiu, Chuan, Zhu, Haitao, Pan, Shuo, Jia, Hao, Kang, Hongyan, Guan, Gongchang, Hui, Rutai, Zhu, Ling, Wang, Junkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373908/
https://www.ncbi.nlm.nih.gov/pubmed/32525286
http://dx.doi.org/10.1002/ehf2.12789