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Requirement for cleavage factor II(m) in the control of alternative polyadenylation in breast cancer cells

Alternative polyadenylation (APA) determines stability, localization and translation potential of the majority of mRNA in eukaryotic cells. The heterodimeric mammalian cleavage factor II (CF II(m)) is required for pre-mRNA 3′ end cleavage and is composed of the RNA kinase hClp1 and the termination f...

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Detalles Bibliográficos
Autores principales: Turner, Rachael E., Henneken, Lee M., Liem-Weits, Marije, Harrison, Paul F., Swaminathan, Angavai, Vary, Robert, Nikolic, Iva, Simpson, Kaylene J., Powell, David R., Beilharz, Traude H., Dichtl, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373993/
https://www.ncbi.nlm.nih.gov/pubmed/32295865
http://dx.doi.org/10.1261/rna.075226.120