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Metabolic labeling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels

Cells adapt to environmental changes, including fluctuations in oxygen levels, through the induction of specific gene expression programs. However, most transcriptomic studies do not distinguish the relative contribution of transcription, RNA processing, and RNA degradation processes to cellular hom...

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Detalles Bibliográficos
Autores principales: Tiana, Maria, Acosta-Iborra, Bárbara, Hernández, Rosana, Galiana, Clara, Fernández-Moreno, Miguel Ángel, Jimenez, Benilde, del Peso, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373995/
https://www.ncbi.nlm.nih.gov/pubmed/32295863
http://dx.doi.org/10.1261/rna.072611.119