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5-methylcytosine modification of an Epstein–Barr virus noncoding RNA decreases its stability

Many cellular noncoding RNAs contain chemically modified nucleotides that are essential for their function. The Epstein–Barr virus expresses two highly abundant noncoding RNAs called EBV-encoded RNA 1 (EBER1) and EBER2. To examine whether these viral RNAs contain modified nucleotides, we purified na...

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Detalles Bibliográficos
Autores principales: Henry, Belle A., Kanarek, Jack P., Kotter, Annika, Helm, Mark, Lee, Nara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373997/
https://www.ncbi.nlm.nih.gov/pubmed/32354721
http://dx.doi.org/10.1261/rna.075275.120