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Codon Usage Optimization in the Prokaryotic Tree of Life: How Synonymous Codons Are Differentially Selected in Sequence Domains with Different Expression Levels and Degrees of Conservation

Prokaryote genomes exhibit a wide range of GC contents and codon usages, both resulting from an interaction between mutational bias and natural selection. In order to investigate the basis underlying specific codon changes, we performed a comprehensive analysis of 29 different prokaryote families. T...

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Detalles Bibliográficos
Autores principales: López, José Luis, Lozano, Mauricio Javier, Fabre, María Laura, Lagares, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374057/
https://www.ncbi.nlm.nih.gov/pubmed/32694138
http://dx.doi.org/10.1128/mBio.00766-20