Dantrolene prevents hepatic steatosis by reducing cytoplasmic Ca(2+) level and ER stress

INTRODUCTION: Our previous studies demonstrated that dantrolene, a ryanodine receptor stabilizer, prevents endoplasmic reticulum (ER) stress in the heart. ER stress is a strong mediator of impaired lipid metabolism in the liver, thereby contributing to fatty liver disease. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Tamitani, Masaki, Yamamoto, Takeshi, Yamamoto, Naoki, Fujisawa, Koichi, Tanaka, Shinji, Nakamura, Yoshihide, Uchinoumi, Hitoshi, Oda, Tetsuro, Okuda, Shinichi, Takami, Taro, Kobayashi, Shigeki, Sakaida, Isao, Yano, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374254/
https://www.ncbi.nlm.nih.gov/pubmed/32715106
http://dx.doi.org/10.1016/j.bbrep.2020.100787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374254/
https://www.ncbi.nlm.nih.gov/pubmed/32715106
http://dx.doi.org/10.1016/j.bbrep.2020.100787

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