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Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells

OBJECTIVES: Adoptive transfer of chimeric antigen receptor (CAR)‐modified T cells is a form of cancer immunotherapy that has achieved remarkable efficacy in patients with some haematological cancers. However, challenges remain in CAR T‐cell treatment of solid tumours because of tumour‐mediated immun...

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Detalles Bibliográficos
Autores principales: Chan, Jack D, von Scheidt, Bianca, Zeng, Bijun, Oliver, Amanda J, Davey, Ashleigh S, Ali, Aesha I, Thomas, Ranjeny, Trapani, Joseph A, Darcy, Phillip K, Kershaw, Michael H, Dolcetti, Riccardo, Slaney, Clare Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374388/
https://www.ncbi.nlm.nih.gov/pubmed/32704371
http://dx.doi.org/10.1002/cti2.1157