Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survival rates remain at < 20%. To improve treatment outcomes...

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Detalles Bibliográficos
Autores principales: Buckley, Amy M., Dunne, Margaret R., Morrissey, Maria E., Kennedy, Susan A., Nolan, Aoife, Davern, Maria, Foley, Emma K., Clarke, Niamh, Lysaght, Joanne, Ravi, Narayanasamy, O’Toole, Dermot, MacCarthy, Finbar, Reynolds, John V., Kennedy, Breandán N., O’Sullivan, Jacintha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374542/
https://www.ncbi.nlm.nih.gov/pubmed/32694701
http://dx.doi.org/10.1038/s41598-020-68777-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374542/
https://www.ncbi.nlm.nih.gov/pubmed/32694701
http://dx.doi.org/10.1038/s41598-020-68777-7

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