A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

Genome–wide association studies (GWAS) have revealed a plethora of putative susceptibility genes for Alzheimer’s disease (AD), with the sole exception of APOE gene unequivocally validated in independent study. Considering that the etiology of complex diseases like AD could depend on functional multi...

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Detalles Bibliográficos
Autores principales: Squillario, Margherita, Abate, Giulia, Tomasi, Federico, Tozzo, Veronica, Barla, Annalisa, Uberti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374579/
https://www.ncbi.nlm.nih.gov/pubmed/32694537
http://dx.doi.org/10.1038/s41598-020-67699-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374579/
https://www.ncbi.nlm.nih.gov/pubmed/32694537
http://dx.doi.org/10.1038/s41598-020-67699-8

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