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Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors

We describe a potential role for thymidine kinase-1, a general marker of cellular proliferation, to act as a prognostic biomarker in patients receiving CDK4/6 inhibitors for advanced hormone receptor-positive, HER2-negative breast cancer, with early data suggesting that it may also provide early ind...

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Detalles Bibliográficos
Autores principales: McCartney, Amelia, Malorni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374612/
https://www.ncbi.nlm.nih.gov/pubmed/32382111
http://dx.doi.org/10.1038/s41416-020-0858-y