Cargando…

The histone lysine methyltransferase SETD8 regulates angiogenesis through HES-1 in human umbilical vein endothelial cells

Histone modifications, including histone lysine methylation, regulate gene expression in the vasculature, and targeting tumor blood vessels through histone modification decreases tumor growth. SETD8, a methyltransferase that catalyzes the mono-methylation of histone H4 lysine 20 is known to promote...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Dong Kyu, Kim, Young Kyu, Park, Sang Wook, Lee, Heejin, Lee, Seul, Kim, Sang A., Kim, Soo Jin, Lee, Junyeop, Kim, Wanil, Min, Sang-Hyun, Yu, Ji Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374624/
https://www.ncbi.nlm.nih.gov/pubmed/32694555
http://dx.doi.org/10.1038/s41598-020-69103-x