Cargando…

The histone lysine methyltransferase SETD8 regulates angiogenesis through HES-1 in human umbilical vein endothelial cells

Histone modifications, including histone lysine methylation, regulate gene expression in the vasculature, and targeting tumor blood vessels through histone modification decreases tumor growth. SETD8, a methyltransferase that catalyzes the mono-methylation of histone H4 lysine 20 is known to promote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Dong Kyu, Kim, Young Kyu, Park, Sang Wook, Lee, Heejin, Lee, Seul, Kim, Sang A., Kim, Soo Jin, Lee, Junyeop, Kim, Wanil, Min, Sang-Hyun, Yu, Ji Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374624/ https://www.ncbi.nlm.nih.gov/pubmed/32694555 http://dx.doi.org/10.1038/s41598-020-69103-x

Ejemplares similares

Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif
por: Binda, Olivier
Publicado: (2019)

Structure, activity and function of the lysine methyltransferase SETD5
por: Li, Mingyang, et al.
Publicado: (2023)

Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts
por: Chen, Fengling, et al.
Publicado: (2021)

The Role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice
por: Lee, Seul, et al.
Publicado: (2020)

Epigenetic Role of Histone 3 Lysine Methyltransferase and Demethylase in Regulating Apoptosis Predicting the Recurrence of Atypical Meningioma
por: Lee, Sang Hyuk, et al.
Publicado: (2015)

Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation
por: Hanna, Courtney W, et al.
Publicado: (2022)

Histone-lysine N-methyltransferase SETD7 is a potential serum biomarker for colorectal cancer patients
por: Duan, Baojun, et al.
Publicado: (2018)

Histone lysine methyltransferase Pr‐set7/SETD8 promotes neural stem cell reactivation
por: Huang, Jiawen, et al.
Publicado: (2021)

The emerging role of lysine methyltransferase SETD8 in human diseases
por: Milite, Ciro, et al.
Publicado: (2016)

The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase
por: Seervai, Riyad N. H., et al.
Publicado: (2020)

Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate
por: Schuhmacher, Maren Kirstin, et al.
Publicado: (2020)

Lysine Ethylation by Histone Lysine Methyltransferases
por: Al Temimi, Abbas H. K., et al.
Publicado: (2019)

The histone methyltransferase SETD2 negatively regulates cell size
por: Molenaar, Thom M., et al.
Publicado: (2022)

Histone Lysine Methylation and Neurodevelopmental Disorders
por: Kim, Jeong-Hoon, et al.
Publicado: (2017)

Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8
por: Ma, Anqi, et al.
Publicado: (2014)

Author Correction: Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate
por: Schuhmacher, Maren Kirstin, et al.
Publicado: (2020)

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
por: Parker, H, et al.
Publicado: (2016)

The histone methyltransferase Setd2 is indispensable for V(D)J recombination
por: Ji, Zhongzhong, et al.
Publicado: (2019)

Histone methyltransferase SETD1A participates in lung cancer progression
por: Du, Mei, et al.
Publicado: (2021)

Histone Methyltransferase SETD2 Is Required for Porcine Early Embryonic Development
por: Shao, Weini, et al.
Publicado: (2022)

Inhibition of histone methyltransferase SETD8 represses DNA virus replication
por: Chen, Lin, et al.
Publicado: (2022)

Chemical Probes of Histone Lysine Methyltransferases
por: Kaniskan, H. Ümit, et al.
Publicado: (2014)

Dynamic changes of SETD2, a histone H3K36 methyltransferase, in porcine oocytes, IVF and SCNT embryos
por: Diao, Yun Fei, et al.
Publicado: (2018)

Histone methyltransferase SETD2: a potential tumor suppressor in solid cancers
por: Chen, Rui, et al.
Publicado: (2020)

The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis
por: Liu, Min, et al.
Publicado: (2021)

A Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer
por: Monteiro, Fátima Liliana, et al.
Publicado: (2022)

The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin
por: Driskell, Iwona, et al.
Publicado: (2012)

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription
por: Carvalho, Sílvia, et al.
Publicado: (2013)

Histone methyltransferase SETD2: An epigenetic driver in clear cell renal cell carcinoma
por: Yu, Mengxue, et al.
Publicado: (2023)

Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes
por: Michurina, Alexandra, et al.
Publicado: (2021)

Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain
por: Lee, Young Min, et al.
Publicado: (2020)

Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis
por: Temimi, Abbas H. K. Al, et al.
Publicado: (2017)

Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis
por: Temimi, Abbas H. K. Al, et al.
Publicado: (2020)

SETD2 and histone H3 lysine 36 methylation deficiency in advanced systemic mastocytosis
por: Martinelli, G, et al.
Publicado: (2018)

Epigenetic Regulation of the Expression of T Cell Stimulatory and Inhibitory Factors by Histone H3 Lysine Modification Enzymes and Its Prognostic Roles in Glioblastoma
por: Lee, Sang Hyuk, et al.
Publicado: (2023)

Downregulation of the histone methyltransferase SETD2 promotes imatinib resistance in chronic myeloid leukaemia cells
por: Sheng, Yaru, et al.
Publicado: (2019)

Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies
por: Lampe, John W., et al.
Publicado: (2021)

Fine-tuning of lysine side chain modulates the activity of histone lysine methyltransferases
por: Al Temimi, Abbas H. K., et al.
Publicado: (2020)

Role of several histone lysine methyltransferases in tumor development
por: LI, JIFU, et al.
Publicado: (2016)

The role of histone lysine methyltransferase NSD3 in cancer
por: Han, Xu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_c8mq1lni88r922bruek41hejo1